Anti-CALD1 Mouse Monoclonal Antibody (CF405S) [clone: h-CALD]

Leverandør: Biotium
Ratings: Ingen bedømmelse

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BNC040819-500 BNC040819-100
BNC040819-500EA 4180 DKK
BNC040819-500 BNC040819-100
Anti-CALD1 Mouse Monoclonal Antibody (CF405S) [clone: h-CALD]
Antistoffer
Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

Type: Primary
Antigen: CALD1
Clonality: Monoclonal
Clone: h-CALD
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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