Anti-ESR2 Mouse Monoclonal Antibody (CF488A) [clone: ESR2/686]

Leverandør: Biotium
Ratings: Ingen bedømmelse

Samlet vurdering
Gennemsntilig vurdering

BNC880686-500 BNC880686-100
BNC880686-500EA 4180 DKK
BNC880686-500 BNC880686-100
Anti-ESR2 Mouse Monoclonal Antibody (CF488A) [clone: ESR2/686]
Antistoffer
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.

Type: Primary
Antigen: ESR2
Clonality: Monoclonal
Clone: Clone ESR2/686
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human
Bestil nu

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Læs mere About VWR