Anti-VCAM1 Mouse Monoclonal Antibody (CF594) [clone: B-K9]

Leverandør: Biotium
Ratings: Ingen bedømmelse

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BNC940304-500 BNC940304-100
BNC940304-500EA 4180 DKK
BNC940304-500 BNC940304-100
Anti-VCAM1 Mouse Monoclonal Antibody (CF594) [clone: B-K9]
Antistoffer
Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.

Type: Primary
Antigen: VCAM1
Clonality: Monoclonal
Clone: B-K9
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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