Anti-CD74 Mouse Monoclonal Antibody (CF568) [clone: LN-2]

Leverandør: Biotium
Ratings: Ingen bedømmelse

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BNC680056-500 BNC680056-100
BNC680056-500EA 4180 DKK
BNC680056-500 BNC680056-100
Anti-CD74 Mouse Monoclonal Antibody (CF568) [clone: LN-2]
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This antibody recognizes a protein of ~35 kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).

Type: Primary
Antigen: CD74
Clonality: Monoclonal
Clone: LN-2
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Baboon, Human, Mouse
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