Anti-CD66 Mouse Monoclonal Antibody (CF488A) [clone: COL-1]

Leverandør: Biotium
Ratings: Ingen bedømmelse

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BNC880002-500 BNC880002-100
BNC880002-500EA 4180 DKK
BNC880002-500 BNC880002-100
Anti-CD66 Mouse Monoclonal Antibody (CF488A) [clone: COL-1]
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This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Type: Primary
Antigen: CD66
Clonality: Monoclonal
Clone: COL-1
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
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