Anti-Ly-6G Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7) [clone: 1A8]

Leverandør: Tonbo Biosciences
Ratings: Ingen bedømmelse

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60-1276-U025 60-1276-U100
60-1276-U025EA 485 DKK
60-1276-U025 60-1276-U100
Anti-Ly-6G Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7) [clone: 1A8]
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The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151: 2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

Type: Primary
Antigen: Ly-6G
Clonality: Monoclonal
Clone: 1A8
Conjugation: PE (Phycoerythrin)-Cy7
Epitope:
Host: Rat
Isotype: IgG2a, kappa
Reactivity: Mouse
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