Anti-ID4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Leverandør: Bioss
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BS-6669R-A647
BOSSBS-6669R-A647EA 6670 DKK
BOSSBS-6669R-A647
Anti-ID4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
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Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1 (1–3), Id2 (4), Id3 and Id4 (5). They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins (1–5). Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since Id1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the Id protein levels fall,More Product Information
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