Anti-RECQL5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Leverandør: Bioss
Ratings: Ingen bedømmelse

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BS-11231R-A680
BOSSBS-11231R-A680EA 6640 DKK
BOSSBS-11231R-A680
Anti-RECQL5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
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RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4) are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higherMore Product Information
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